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    Fam133b family with sequence similarity 133, member B [ Mus musculus (house mouse) ]

    Gene ID: 68152, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Fam133bprovided by MGI
    Official Full Name
    family with sequence similarity 133, member Bprovided by MGI
    Primary source
    MGI:MGI:1915402
    See related
    Ensembl:ENSMUSG00000058503 AllianceGenome:MGI:1915402
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2900022K02Rik; 5830415L20Rik
    Summary
    Is expressed in cerebral cortex ventricular layer. Orthologous to several human genes including FAM133B (family with sequence similarity 133 member B). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 10.0), CNS E14 (RPKM 7.3) and 27 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    5 A1; 5 2.22 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (3593833..3620548)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (3543833..3570548)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_12301 Neighboring gene STARR-seq mESC enhancer starr_12302 Neighboring gene predicted gene, 36548 Neighboring gene STARR-seq mESC enhancer starr_12303 Neighboring gene STARR-seq mESC enhancer starr_12305 Neighboring gene cyclin dependent kinase 6, opposite strand transcript 1 Neighboring gene STARR-seq mESC enhancer starr_12306 Neighboring gene STARR-seq mESC enhancer starr_12307 Neighboring gene STARR-positive B cell enhancer ABC_E10299 Neighboring gene STARR-positive B cell enhancer ABC_E2150 Neighboring gene cyclin dependent kinase 6 Neighboring gene STARR-positive B cell enhancer ABC_E2736 Neighboring gene STARR-seq mESC enhancer starr_12309 Neighboring gene predicted gene, 29868 Neighboring gene STARR-seq mESC enhancer starr_12311 Neighboring gene STARR-positive B cell enhancer ABC_E4741 Neighboring gene RIKEN cDNA 1700109H08 gene Neighboring gene STARR-seq mESC enhancer starr_12313 Neighboring gene STARR-seq mESC enhancer starr_12314 Neighboring gene STARR-positive B cell enhancer ABC_E429 Neighboring gene RNA binding motif protein 48 Neighboring gene peroxisomal biogenesis factor 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis. Sansom SN, et al. PLoS Genet, 2009 Jun. PMID 19521500, Free PMC Article
    2. ATG5 is required for B cell polarization and presentation of particulate antigens. Arbogast F, et al. Autophagy, 2019 Feb. PMID 30196744, Free PMC Article
    3. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
    4. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
    5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    protein FAM133B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001042501.1 → NP_001035966.1  protein FAM133B

      See identical proteins and their annotated locations for NP_001035966.1

      Status: VALIDATED

      Source sequence(s)
      AC090443, AK008115, BY711248, CK791263
      Consensus CDS
      CCDS39000.1
      UniProtKB/Swiss-Prot
      B2RVR0, Q78HY5, Q9CVI2
      Related
      ENSMUSP00000111189.4, ENSMUST00000115527.8

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      3593833..3620548
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_026583.2: Suppressed sequence

      Description
      NM_026583.2: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9CVI2.3 GenPept UniProtKB/Swiss-Prot:Q9CVI2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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